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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd2acf9326b7ab34e74dd34bf101bff3f6294bd54f4870e4d85088aaf42084d' 
  AND token = 'GypDKnDWNOhXQeEC4e3Fm+PPSFZ8HABPRc8c8R7SGCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}