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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c12518ecb9b008be3c4e6a0642f15ea3c8a6b6a61cd19457115a61f0b11855e' 
  AND token = 'F34h5vy+lKS1LJOUUpIdFeuIeywZ77wEDJZ2OrlfJCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}