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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3451108ec8fde5470cc2b43d6c21d892f598c5244a4ead76d2f8c4f2b6fd0b63' 
  AND token = 'KiMJo0f00qy/m+4k890sp93LS/7NdZ+7hF/F2SlLn5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}