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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aa039c22ca85eaa14646b71ea3e6f3ce4dac35d23496d224ac8b5c378e902d9' 
  AND token = 'jTTlYHHDiAeV/vpvy+CKA02aYjcxSzAGLrbrI/C1DY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}