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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f9e09dc2c62ffd99876579f8ed7a597382369fe08b8d4b8ef4d45ed9172c46' 
  AND token = '1mtI8Rtk6I9/gGHwAyKy/hWFn/sRe9QCu7SOktIHJpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}