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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef9016c0f4e9b2ba71483c1183ebc273551c14be3707cb00bbb0997beee1fe3' 
  AND token = 't/+LlbHesfWy1tUwwC5HhYK5wX9AkyMZArfkkfNAwO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}