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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495d7a24abd06bd63ee8e101e04fcebd3578af6efc208383a180b73f07e6d2f4' 
  AND token = 'bc0kRjcsZDK2JOKcpwaQYZJhRFW9t1xXU4k0SIte5yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}