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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289fe196d69181699957c90e11a79730fd509b8d3cfff3f0f81c4076c6069e1b' 
  AND token = 'TlPLCu31vWFt7qoQ/aPODPCM4XmpJSv4y0N798hk7MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}