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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21564325669918b388ca80b71311c2a75ede380213394ae7ae7c2ec0d81c007b' 
  AND token = '5x/tZBhcAjpkfC69CVBr+CXsnp1NCssR4LCw0VUIujQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}