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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376fb18649356236f43c3008c4a205455b4ca4608713c6e1446298798f7ad20b' 
  AND token = 'ynA1wLhrS2UadOrD98CIBvCCOavDwyWWCvUxcdT1GVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}