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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1046f6b4459b41e865f904c30542d7cdb4a6259fa9aae9814661c328602389' 
  AND token = 'bHLpdXhrKO5koG3Nk7N/P/OcU+VuW8aAe3vfyZ0yA80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}