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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1a67272214a1422506d119eef774af7cd5752038683b7dfe4edf07a99a49f4' 
  AND token = '2YzQFftdBuiNLyp7unnIrINBLSHQHkwL6iOyMQJotNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}