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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e425d44c591c7a9609863be58add3a840a560a00072ebd90d6f1a8b792b92f' 
  AND token = 'dfvwKlxESp/vcOw5siUJ/3WtxkhDjzEWPi14U8UFbO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}