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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef793efe3e24a90c1a8dc1f777010453df8220f6d28b067829f9b751e3f7eee2' 
  AND token = 'Ylo86zC7poIsOIuaU7LHvp2ycNQfEH9dcgLBaOHstjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}