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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b761f21688bcb132ca8dd85a4353b6e216784036b8b7a933d16058f87d729ab' 
  AND token = '/TRW4QF8NLuDPPuEIQv5oDxGepCAXaOHWolK1bqZfvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}