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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8af8bbaccc6b7bb50041018a2049d3750bb81536cc232ab1d96ecc4269b9c98' 
  AND token = '9B6rkxkgQOZkqURmVN6UZCh4YSZjU0jY2fagJic8zT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}