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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d963b11b5b56787cf0b786f4787dfb9e76b105fcc7e5f2a8ae442cc734b6598' 
  AND token = 'OdpS+fYXNw59t+hVt01gVCN5tvqPZAdIfwd9GFWyyfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}