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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd870f8aee664862fa67a008d5c8bba80b2f0c507db6b2c625e5c4335226543ec' 
  AND token = '2ay6JxnsU23aDw3KxiswkFcxZUCU5IgbxjnqIS4Zw7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}