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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e49a98f3425da72e5eaac0b3ef70e7dfd129da79c005279310ed471a410587' 
  AND token = '0kNQ6Fmd1kR9s2MzggxBdWzQ1eKgTKTjKDMv9/alDS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}