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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1152e204246a7465b6291d6674981de5a3b6c53b2fc7001d02438d4176bc89' 
  AND token = 'DR6NuXk6l9wg10iH2LlAGrQa1F4bvB3jVx2R6rUs3IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}