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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467d79f5bc463c6d33988161b0f6adb2007cc6ab89ad2893aa8617a670cb5877' 
  AND token = 'pzSz1bwo06+eS9D2N2Es/2QeTspQ7Kgk3l3Ik76qqSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}