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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34434ce550d7c9244b9542a350f6ce0f91fcb387227adcfd4ee2814b884dd6bb' 
  AND token = '6z31h6zY0pG/hs4wyD5KaBS6EG0e4ukQ2y7gUv9VAdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}