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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d310d5fe3c9647b2d8cef76673511ca9fe3a0ef3186bf3e050dea8e55c29d4' 
  AND token = 'hALJYp0Qjh8fIQYUnvomhj4D6k4IEY9sNRkKmru/HM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}