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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d4a917cefda0f7043734a826f8f49ddc6c08dcd0686e646b589e72d0c8c264e' 
  AND token = '16xCowboPueg4QLuwV7LNrHSPrRtRW4nH2SkTo0KycI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}