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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fa6650efa02c33050bdff4c77e7810a052950d71c91f8e64b8b0a87da43fd8c' 
  AND token = 'bhWSl9hDUFDqmWY75bimJ06dRVPqBroqIBUNCtQ6NIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}