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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ed723a9e4262f611a89eae7fbb2ce88fa31f28665fcfb962b1b1f490f78732' 
  AND token = 'pv2WiReH0WYLDp7Af4lwNBWFASvGYOoZC7iIqR6mq2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}