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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1b8e9824a5255e41f2d405a7e51190074c8efb741edfca15a7b24eded4863d' 
  AND token = 'jIOvbIb670rgMAykQwwm+YVmweXoPPL1gyhzccqj2vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}