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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9105c6a09ef739213a0c0153fa234c33e7b8b0331efd1731eef9eb12f13afa45' 
  AND token = 'csz2tAHJdb0Rzox+2LOkgrgxC2ZJM8fA+sn5c3BWgWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}