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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644d1a8331ec5f99c1941091e3d3ba52492e5a0c1db952a051e41177ba4619ff' 
  AND token = 'kuxMDmD+49tki20tvGlKnBilDv7e9aacV88dxwlXUGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}