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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '171663c5eb4acd7028be1d4fef0f7ea796c0aaef031cabb75fe05abb847815f3' 
  AND token = 'Ae+3qQRmVaW/TWo4H0nNgH7fuGfQQBFC1j0SK0MesU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}