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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8506f84d36a644f700ff12ae50ad53302473007cd70a34009f0ad5d7ce4e15b7' 
  AND token = 'i9kUw83SY5CmwPPP+QRzfC37SrptMR7yGWqQ1EX2mtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}