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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a4f38e3e8304de0544826aba3ed2d006c9643f3d78c9c24a816b7a59a133fd0' 
  AND token = 'VVZG0ZKsoLmAG4D3EGjxGawqkYiGNwAPxd549QiihrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}