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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28052fa3bc50287d3bd66baa3ca76da10f97414520abbb208748d30d0806f69' 
  AND token = 'nIBfvDEQCve105YK1JXpQ1ITq4KZ8T3+02wFUyFfQVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00125

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}