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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1184be0f1c630054d29f3711aac1909fcd81e092d22f88a4d8fe04801c4bdd' 
  AND token = 'P0O4TsiN/qaBCU25SIBcMrK97EDHKHVGEtVtnXSYWnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}