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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3335ff1a3cbde363c7d223c5c744f3e6592019e67e56aa03beca9096ed78bda' 
  AND token = '7XXjY3dIrK+gipCJ+dacEIEvgg7ObOAYJ+83Rh2SjA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}