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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '263e7f50184bdec8af41dba2ddc8ac5a592ee142744753801f3020bf3678e9f5' 
  AND token = 'KYbVhHsZpR4Q21K+AYwoPL2+al3jn+Ec4tcAJSTWvM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}