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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05717ea2be218b72fc7aaeb15a578732fdf706a189d39ee289703b41d87ab2b0' 
  AND token = 'kUkPvtu3tdesPeOB+Tv4D6BBS3pyn/otqVzrGkNAW7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}