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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da65a2524e4112af3d4b4fbda24614118a96b8e8962e9604f0a2bf8e52cbb195' 
  AND token = 'nSA3SL3/t3zZjMvIUzVC3UwF4Bg0McIJEK8jsAIIgBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}