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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfdae007f2e3b058d0d9ea86dd6a7e49d3d596b757942a03b0b960f26de94cf' 
  AND token = 'PDMsN8plHHbnvZQ8nw7GOjstkh2pX6eBtdyo49nP7Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}