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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03011342389eb519a2fee3b076e7a456376ecd590c3c3016031b69fd92c81da8' 
  AND token = 'P08Jiw/JQqE+FpH/GHX5w4Zd3aBytHDk3b6DRy+xPlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}