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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2656bf988ca9728c12c1ff47df7330ad0fb4054adefbe08a0b9eb86dccd66066' 
  AND token = 'zYeAMQPJqMADwpZF+s81r6b7zut9hZBQN80e6Uotx5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}