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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581f295ed216b425602c4cec8dd4bba8b7c61a2ea6f33c3725f6aaf234e6dac8' 
  AND token = 'Ph6jvqvEBuPgp/RBp6mv8sWR3r2i6THqlVII41Eqdbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}