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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a41251e03421db7b8cb5db63eb91f6e7e4816dd651bd33961f4ed1a30c6465d' 
  AND token = 'IXM0VoifaEwmOIGM6MRGVGymMOMho8nU1AOMPWSOR40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}