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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375dccf3810a23a2cb5257ba2cbfaa94925edfade67caf920763ca4d95fe4351' 
  AND token = 'dseDuq3B+iOoX+mMCFae2wbgPozHei6f3h++lWIgrw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}