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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4087e27f8354397bb6f3e0ef9bfda249772a5bcbb95867f82a2b52a09360327' 
  AND token = 'tsy7Fz3UM+yJwm5CaxcmmAVSAmrqEMGOilwzx9oxm8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}