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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f766763cf42dbea80ab1f137239fba215385b604c4437fa0dab50260b81e604' 
  AND token = 'JerrG8YTeHI4StTJ1V4dPig8kggBJYKzWehQYLXNPmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}