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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ffa2183807b276a0133e984aab56dcb0a9028f88179d74b1d4e824cc03aad3e' 
  AND token = '+kqNVJtIA1rbDj7oskZvr5FJh9UpOfIfWF9yJW1Nb4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}