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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e93c9a3a13eca998d673a2eadc8b52d754d2bbaf41a0f792166cd13b8d88d1' 
  AND token = 'i8E4NHBD1E1Wp+uwY4CfEORwxUIdnQsDRqS4c8XCPGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}