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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cbe49a02071c65a888521b46c001bce4a728c37746815a140ee9c9f2bbdf7da' 
  AND token = '9n2YZRSjqpMSyotkMCbQD5Q1AQABkvokkNRlZZlfETw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}