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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde62c020f5ff4b80f0b95b94217631cd88ee532b490366425d5333d4ac70140' 
  AND token = 'VPX2nw1veRz4E/gY0cxLqraXfV0h+jM6gSr5zLpCMTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}